References

List of publications in peer-reviewed journals

Ritskes-Hoitinga J & Beynen AC: Atherosclerosis in the rat. Artery (1988) 16: 25-50.

Ritskes-Hoitinga J, Lemmens AG, Danse LHJC & Beynen AC: Phosphorus-induced nephrocalcinosis and kidney function in female rats. Journal of Nutrition (1989) 119: 1423-1431.

Ritskes-Hoitinga J, Lemmens AG & Beynen AC: Nutrition and kidney calcification in rats. Laboratory Animals (1989) 23: 313-318.

Ritskes-Hoitinga J & Beynen AC: Nierverkalking bij de rat. Biotechniek (1989) 28: 89-90.

Adams C, Ritskes-Hoitinga J, Lemmens AG & Beynen AC: Dietary restriction of phosphorus and nephrocalcinosis in two inbred strains of rats. Nutrition Reports International (1989) 40: 923-929.

Schoenmakers ACM, Ritskes-Hoitinga J, Lemmens AG & Beynen AC: The influence of dietary phosphorus restriction on calcium and phosphorus metabolism in rats. International Journal for Vitamin and Nutrition Research (1989) 59: 200-206.

Ritskes-Hoitinga J, Mathot JNJJ & Beynen AC: Commerciële voeders en nierverkalking bij de rat. Biotechniek (1990) 29: 87-89.

Van Camp I, Ritskes-Hoitinga J, Lemmens AG & Beynen AC: Diet-induced nephrocalcinosis and urinary excretion of albumin in female rats. Laboratory Animals (1990) 24: 137-141.

Henskens YMC, Ritskes-Hoitinga J, Mathot JNJJ, Van Camp I & Beynen AC: The influence of dietary lactose on phosphorus-induced nephrocalcinosis in female rats. International Journal for Vitamin and Nutrition Research (1991) 61: 77-86.

Ritskes-Hoitinga J, Mathot JNJJ, Danse LHJC & Beynen AC: Commercial rodent diets and nephrocalcinosis in weanling female rats. Laboratory Animals (1991) 25: 126-132.

Soeterboek SJAJ, Ritskes-Hoitinga J, Lemmens AG & Beynen AC: Phosphorus-induced nephrocalcinosis in female rats: a study on regression and clinical abnormalities. Laboratory Animals (1991) 25: 258-262.

Grooten HNA, Ritskes-Hoitinga J, Mathot JNJJ, Lemmens AG & Beynen AC: Dietary fluoride prevents phosphorus-induced nephrocalcinosis in female rats. Biological Trace Element Research (1991) 29: 147-155.

Kootstra Y, Ritskes-Hoitinga J, Lemmens AG & Beynen AC: Diet-induced calciuria and nephrocalcinosis in female rats. International Journal for Vitamin and Nutrition Research (1991) 61: 100-101.

Van Lith HA, Haller M, Ritskes-Hoitinga J & Beynen AC: Decreased plasma esterase-1 activity in rats fed a high-phosphorus diet. International Journal for Vitamin and Nutrition Research (1991) 61: 98-99.

Ritskes-Hoitinga J & Beynen AC: Nephrocalcinosis in the rat: a literature review. Progress in Food and Nutrition Science (1992) 16: 85-124.

Ritskes-Hoitinga J, Mathot JNJJ, Van Zutphen LFM & Beynen AC: Inbred strains of rats have differential sensitivity to dietary phosphorus-induced nephrocalcinosis. Journal of Nutrition (1992) 122: 1682-1692.

Ritskes-Hoitinga Merel, Bosland Maarten C, De Greeve Paul & Van Zutphen Bert FM: Legislation and animal experimentation in the Netherlands and the US: is there a difference in approach? Lab Animal (1992) 21: 28-37.

Sterck JGH, Ritskes-Hoitinga J & Beynen AC: Inhibitory effect of high protein intake on nephrocalcinogenesis in female rats. British Journal of Nutrition (1992) 67: 223-233.

Beynen AC & Ritskes-Hoitinga J: Fatty acid composition of commercial rodent diets Scandinavian Journal of Laboratory Animal Science (1992) 19: 93-94.

Ritskes-Hoitinga J, Mathot JNJJ, Lemmens AG, Danse LHJC, Meijer GW, Van Tintelen G & Beynen AC: Long-term phosphorus restriction prevents corticomedullary nephrocalcinosis and sustains reproductive performance but delays bone mineralization in rats. Journal of Nutrition (1993) 123: 754-763.

Deckere EAM, de Fouw NJ, Ritskes-Hoitinga J, van Nielen WGL & Blonk CG: Effect of atherosclerotic diet on lipoprotein cholesterol profile in the F1B hybrid hamster. Atherosclerosis (1993) 103: 291-294.

Kloots WJ, van Amelsvoort JMM, Brink EJ, Ritskes J & Remie R: Technique for creating a permanent cecal fistula in the rat. Laboratory Animal Science (1995) 45(5): 588-591.

Ritskes-Hoitinga J, Meijers M, Timmer WG, Wiersma A, Meijer GW & Weststrate JA: Effects of two dietary fat levels and four dietary linoleic acid levels on mammary tumor development in Balb/c-MMTV mice under ad libitum feeding conditions. Nutrition and Cancer (1996) 25: 161-172.

Ritskes-Hoitinga J, Meijers M, Meijer GW & Weststrate JA: The influence of dietary linoleic acid on mammary tumour development in various animal models. Scand. J. LAS (1996) 23: 463-469.

Van Ruiven R, Meijer GW, van Zutphen LFM & Ritskes-Hoitinga J: Adaptation period of laboratory animals after transport: a review. Scandinavian Journal for Laboratory Animal Science (1996) 23: 185-190.

Van Ruiven R, Meijer GW, Wiersma A, Baumans V, van Zutphen LFM & Ritskes-Hoitinga J: The influence of transportation stress on selected nutrititional parameters to establish the necessary minimum period for adaptation in rat feeding studies. Laboratory Animals (1998) 32: 446-456.

Ritskes-Hoitinga J, Verschuren PM, Meijer GW, Wiersma A, van de Kooij A, Timmer WG, Blonk CG & Weststrate JA: The association of increasing dietary concentrations of fish oil with hepatotoxic effects and a higher degree of aorta atherosclerosis in the ad lib-fed rabbit. Food and Chemical Toxicology (1998), 36, 663-672.

Bollen PJA, Madsen LW, Mortensen JT, Ritskes-Hoitinga J & Hansen AK: Investigation of the involvement of Candida albicans in hyperkeratosis of the Göttingen minipig. Scandinavian Journal for Laboratory Animal Science (1998), 25(3), 150-153.

Van den Broek, FAR, Bakker R, den Bieman M, Fielmich-Bouman AXM, Lemmens AG, van Lith HA, Nissen I, Ritskes-Hoitinga J, van Tintelen G & van Zutphen LFM: Genetic analysis of dystrophic cardiac calcification in DBA/2 mice. Biochemical and Biophysical Research Communications 1998;253: 204-208.

Ritskes-Hoitinga J, Meijers M & van Herck H: Bacteriological quality and intake of acidified drinking water in Wistar rats is pH-dependent. Scandinavian Journal for Laboratory Animal Science (1998), 25(3), 124-128.

Krohn TC, Ritskes-Hoitinga J & Svendsen P: The effects of feeding and housing on the behaviour of the laboratory rabbit. Laboratory Animals (1999), 33, 101-107.

Kobæk-Larsen M, Thorup I, Diederichsen A, Fenger C & Ritskes-Hoitinga J: Review of colorectal cancer and its metastases in rodent models – comparative aspects with those in humans. Comparative Medicine 2000; 50(1): 16-27.

Rasmussen C, Ritskes-Hoitinga J. An alternative method for rat fixation when giving subcu­taneous, intramuscular and intraperitoneal injections (Camilla’s method). Scandinavian Journal for Laboratory Animal Science 1999;26(3): 156-159.

Ritskes-Hoitinga J, Bräutigam J, Kaliste-Korhonen E, Smith A. Evaluation of quality systems for animal units: report of the Scand-LAS working group. Scandinavian Journal for Laboratory Animal Science 1999;26(3): 117-120

Ritskes-Hoitinga J, Schledermann C. A pilot study into the effects of various dietary restriction schedules in rabbits. Scandinavian Journal for Laboratory Animal Science 1999;26(2): 66-74.

Kobæk-Larsen M, Fenger C, Hansen K, Nissen I, Diederichsen A, Thorup I, den Bieman M, Vach W, Ritskes-Hoitinga J. Comparative studies of the histopathology of azoxymethane-induced colonic tumors in three inbred rat strains. Comparative Medicine 2002 52(1) 50-57.

Van den Broek F.A.R., Ritskes-Hoitinga J. and Beynen A.C. Influence of excessive fluoride consumption on the severity of dystrophic cardiac calcification in DBA/2 mice. Biological Trace Element Research 2000, 78, 191-203.

Stub C, Ritskes-Hoitinga J, Thon R, Hansen CK, Hansen AK. Fluctuating asymmetry in mice and rats: evaluation of the method. Laboratory Animals 2002, 36, 193-199.

Thon R, Lassen J, Hansen AK, Jegstrup IM, Ritskes-Hoitinga J. Welfare evaluation of genetically modified mice in Denmark. An inventory study of the reports from 1998 to the Animal Experiments Inspectorate. Scandinavian Journal for Laboratory Animal Science 2002, 29(1) 45-55.

Ritskes-Hoitinga J. The need for defined diets and refined feeding methods. Scandinavian Journal for Laboratory Animal Science 2001, 28(1), 51-54.

Stub C, Bratbo Soerensen D, Jegstrup IM, Ritskes-Hoitinga M & Kornerup Hansen A. Fluctuating asymmetry of teeth is not a reliable indicator for assessing stress in rats. Scandinavian Journal for Laboratory Animal Science 2002, 29, 149-153.

Jegstrup I, Thon R, Hansen AK & Ritskes-Hoitinga M. Characterization of transgenic mice – a comparison of protocols for welfare evaluation and phenotype characterization of mice with a suggestion on a future certificate of instruction. Laboratory Animals 2003, 37, 1-9.

Ritskes R, Ritskes-Hoitinga M, Stødkilde-Jørgensen H, Baerentsen K & Hartman T. MRI scanning during Zen meditation: the picture of enlightenment? Journal of Constructivism 2003, 8, 85-89.

Zhou J, Moeller J, Ritskes-HoitingaJ, LarsenML, Austin RC, Falk E. Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice. Atherosclerosis 2003, 168, 255-262.

Moeller Soerensen N, Kobaek-Larsen M, Bonné A, van Zutphen B, Fenger C, Kristiansen K, Ritskes-Hoitinga M. Analysis of beta-catenin, Ki-ras, and microsatellite stability in azoxymethane-induced colon tumors of BDIX/Orl Ico rats. Comparative Medicine 2003, 53(6), 633-638.

Zhou J, Werstuck GH, Lhotak S, de Koning AB, Sood SK, Hossain GS, Moeller J, Ritskes-Hoitinga M, Falk E, Dayal S, Lentz SR, Austin RC. Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice. Circulation 2004, 110(2), 207-213.

Ritskes-Hoitinga J, Grooten HN, Wienk KJ, Peters M, Lemmens AG, Beynen AC. Lowering dietary phosphorus concentrations reduces kidney calcification, but does not adversely affect growth, mineral metabolism, and bone development in growing rabbits. Brit. J. Nutr. 2004, 91(3), 367-376.

Ritskes-Hoitinga M, Skott O, Uhrenholt TR, Nissen I, Lemmens I, Beynen AC: Nephrocalcinosis in rabbits – a case study. Scandinavian J. for  Laboratory Animal Science 2004, 31, 143-148.

Kobaek-Larsen M, Rud L, Oestergaard-Soerensen F, Ritskes-Hoitinga J. Laparoscopy of rats with experimental liver metastases: a method to assess new humane endpoints. Laboratory Animals 2004, 38, 162-168.

Kobaek-Larsen M. Diederichsen A, Agger R, Nissen I, Hokland M, Zeuthen J, Ritskes-Hoitinga J. Immunohistochemical characterization of the immune response towards azoxymethane-induced colon tumours in the BDIX inbred rat strain. APMIS 2004, 112, 698-707.

Kobaek-Larsen M, Fenger C, Ritskes-Hoitinga J. Secondary effects induced by the colon carcinogen azoxymethane in BDIX rats. APMIS 2004, 112, 319-29.

Howard B, van Herck H, Guillen J, Bacon B, Joffe R, Ritskes-Hoitinga M. Report of the FELASA working group on evaluation of quality systems for animal units. Laboratory Animals 2004, 38, 103-118.

Stub C, Thon R, Ritskes-Hoitinga M, Hansen AK. Renal epithelial proliferation and its clinical expression in Brown Norway (BN) rats. Laboratory Animals 2004, 38, 85-91.

Stub C, Ritskes-Hoitinga M, Olsen A K, Krohn T C, Kornerup Hansen A. Fluctuating asymmetry in relation to single housing versus group housing in three inbred mouse strains. Scand J LAS 2004, 31(4), 245-249.

Voipio H-M, Kaliste E,j Hirsjärvi P, Nevalainen T, Ritskes-Hoitinga M. Nordic-European workshop on ethical evaluation of animal experiments. Scand J LAS 2004, 31(4), 251-267.

Bollen PJA, Madsen LW, Meyer O, Ritskes-Hoitinga J. Growth differences of male and female Göttingen minipigs during ad libitum feeding – a pilot study. Laboratory Animals: 2005, 39, 80-93.

Jegstrup IM, Vestergaard R, Ritskes-Hoitinga M. Nest building behaviour in male rats in three inbred strains: BDIX/Orl Ico, BN/HsdCpb and Lewis/Mol. Animal Welfare 2005, 14, 149-156.

Kobæk-Larsen M, Christensen L P, Vach W, Ritskes-Hoitinga J, Brandt K. Inhibitory effects of feeding with carrots or (-)-falcarinol on development of Azoxymethane-induced preneoplastic lesions in the rat colon. J of Agricultural and Food Chemistry 2005, 53(5), 1823-1827.

Soerensen DB, Stub C, Jegstrup IM, Ritskes-Hoitinga M, Hansen AK. Fluctuating asymmetry in relation to stress and social status in inbred male Lewis rats. Scand J LAS 2005, 32(2), 117-123.

Bollen PJA, Remie R, Kloots W, Barfred L, Salomon S, Ritskes-Hoitinga M. Post-graduate teaching in microsurgery using a combination of alternative non-animal and in vivo methods. Scand J LAS 2005, 32(3), 183-187.

Bollen PJA, Lemmens AG, Beynen AC, Meyer O, Ritskes-Hoitinga J. Bone composition in male and female Göttingen minipigs fed variously restrictedly and near ad libitum. Scand J LAS (2006), 33(3), 1-10.

Nygaard Jensen M, Ritskes-Hoitinga M. How isoflavone levels in common rodent diets can interfere with the value of animal models and with experimental results. Laboratory animals (2007) 41 (1), 1-18.

Sorensen DB, Stub C, Jensen HE, Ritskes-Hoitinga M, Hjorth P, Ottesen JL, Hansen AK. The impact of tail tip amputation and ink tattoo on C57BL/6JBomTac mice. Laboratory Animals (2007) 41(1), 19-29.

Sommers MG, Nguyen NK, Veening JG, Vissers KC, Ritskes-Hoitinga M, van Egmond J. Suppression of noxious-induced c-fos expression in the rat lumbar spinal cord by isoflurane alone or combined with fentanyl. Anesthesia and Analgesia (2008) 106(4), 1303-1308.

Leenaars M, Savenije B, Nachtegaal A, van der Vaart L, Ritskes-Hoitinga M. Assessing the search for and implementation of the three Rs: a survey among scientists. ATLA (2009) 37(3), 297-305.

Thon R, Vondeling H, Lassen J, Hansen AK, Ritskes-Hoitinga M. An interview study of phenotypic characterization of genetically-modified mice. Laboratory Animals (2009) 43, 278-283,

Hooijmans CR, Leenaars M, Ritskes-Hoitinga M. A gold standard publication checklist for improving quality of animal studies, fully integrate the 3Rs and to make systematic reviews feasible. ATLA (2010, 38, 167-182).

Hooijmans CR, Blom HJ, Oppenraaij-Emmerzaal D, Ritskes-Hoitinga M, Kiliaan AJ.  S-adenosylmethionine and S-adenosylhomocysteine levels in the aging brain of APP/PS1 Alzheimer mice.  Neurol Sci. 2009 30(5), 439-45.

Sommers, M.G.J., van Egmond, J, Veening, J.G., Vissers, K.C.P. & Ritskes-Hoitinga, J. (2009). Alternatives for Analgesiometric Tests in Animals: The Feasibility to Reduce Discomfort by Anaesthesia. Scandinavian Journal of Laboratory Animal Science, 36(3), 1-11.

Carlijn R Hooijmans, Alice Tillema, Marlies Leenaars, Merel Ritskes-Hoitinga. Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed. Laboratory Animals (2010)

Hooijmans et al. Improving planning, design, reporting and scientific quality of animal experiments by using the GSPC in addition to the ARRIVE guidelines. Commentary Brit. J. Pharmacology 2011, 162, 1259-1260.

Hooijmans et al. The GSPC for improved design, reporting and scientific quality of animal studies. GSPC versus ARRIVE guidelines. Letter to the editor Laboratory Animals 2011, 45, 61.

Hooijmans et al. Enhancing search efficiency by means of a search filter for finding all studies on animal experimentation in PubMed. Laboratory Animals 2010, 44(3), 170-175 (open access).

De Vries et al. A search filter for increasing the retrieval of animal studies in Embase.   Laboratory Animals 2011, 45(4), 268-70.

Leenaars et al. A step-by-step guide to systematically identify all relevant animal studies. Laboratory Animals 2012 , 46(1), 24-31.

Van Luijk J, Cuijpers Y, van der Vaart L, Leenaars M, Ritskes-Hoitinga M et al. A survey on the 3Rs among scientists in the Netherlands – current practice and directions for improvement. ATLA 2011, 39(5), 429-47.

Van Luijk J, Leenaars M, van Dongen AM, van der Vaart L, Ritskes-Hoitinga M. Outcomes of a Dutch workshop on improvements for the 3Rs in daily practice. ALTEX, 2012;29(4):440-3.

Hooijmans Carlijn R, Pieternel C.M. Pasker – de Jong, Rob B.M. de Vries, Merel Ritskes-Hoitinga. The effects of long-term omega-3 fatty acid supplementation on cognition and Alzheimer’s pathology in animal models of Alzheimer’s disease: a Systematic Review and Meta-Analysis. J. Alzheimer disease 2012, 28(1):191-209.

Hooijmans CR, de Vries RB, Rovers MM, Gooszen HG, Ritskes-Hoitinga M. The effects of probiotic supplementation on experimental acute pancreatitis: a systematic review and meta-analysis. PLoS One. 2012;7(11):e48811. doi: 10.1371/journal.pone.0048811. http://www.ncbi.nlm.nih.gov/pubmed/23152810

Hooijmans CR, Rovers M, de Vries RB, Leenaars M, Ritskes-Hoitinga M. An initiative to facilitate well-informed decision-making in laboratory animal research: report of the First International Symposium on Systematic Reviews in Laboratory Animal Science. Lab Anim. 2012 Oct;46(4):356-7. doi: 10.1258/la.2012.012052.

Moraal M, Leenaars PP, Arnts H, Smeets K, Savenije BS, Curfs JH, Ritskes-Hoitinga M. The influence of food restriction versus ad libitum feeding of chow and purified diets on variation in body weight, growth and physiology of female Wistar rats. Lab Anim. 2012 Apr;46(2):101-7. doi: 10.1258/la.2011.011011

De Vries RB, Buma P, Leenaars M, Ritskes-Hoitinga M, Gordijn B. Reducing the number of laboratory animals used in tissue engineering research by restricting the variety of animal models. Articular cartilage engineering as a case study. Tissue Engineering Part B Rev June 25, 2012: 18(6), 427-435.

De Vries RBM, Leenaars M, Tra J, Huijbregtse R, Bongers E, Jansen JA, Gordijn B, Ritskes-Hoitinga M. The potential of tissue engineering for developing alternatives to animal experiments. A systematic review. J. Tissue Engineering and Regenerative Medicine. 2013. DOI: 10.1002/term.1703. http://www.ncbi.nlm.nih.gov/pubmed/23554402

Hooijmans CR, Ritskes-Hoitinga M (2013) Progress in Using Systematic Reviews of Animal Studies to Improve Translational Research. PLoS Med 10(7): e1001482. doi:10.1371/journal.pmed.1001482.

Van Luijk J, Cuijpers Y, van der Vaart L, de Roo TC, Leenaars M, Ritskes-Hoitinga M. Assessing the application of the 3Rs: a survey among animal welfare officers in The Netherlands. Lab Anim. 2013 Jul;47(3):210-9.

Wever KE, Menting TP, Rovers M, van der Vliet JA, Rongen GA, et al. (2012) Ischemic Preconditioning in the Animal Kidney, a Systematic Review and Meta-Analysis. PLoS ONE 7(2): e32296. doi:10.1371/journal.pone.0032296

Judith van Luijk, Marlies Leenaars, Carlijn Hooijmans, Kim Wever, Rob de Vries, and Merel Ritskes-Hoitinga. Towards evidence-based translational research: The pros and cons of conducting systematic reviews of animal studies.  ALTEX 2013, 30(2), 256 – 257

De Vries RB, Hooijmans CR, Tillema A, Leenaars M, Ritskes-Hoitinga M. Letter to the editor, Updated version of the Embase search filter for animal studies. Laboratory Animals 2014;48(1):88.

van den Brink I, van de Pol F, Vaneker M, Kox M, Schellekens WJ, Ritskes-Hoitinga,M, Scheffer GJ Mechanical ventilation of mice under general anesthesia during experimental procedures. Lab Anim (NY). 2013 Jul;42(7):253-7. doi: 10.1038/laban.252.

Griffin G, Clark JM, Zurlo J, Ritskes-Hoitinga M. Scientific uses of animals: harm-benefit analysis and complementary approaches to implementing the three Rs. Revue scientifique et technique (International Office of Epizootics). 2014;33(1):265-72.

Hooijmans CR, IntHout J, Ritskes-Hoitinga M, Rovers MM. Meta-analyses of animal studies: an introduction of a valuable instrument to further improve healthcare. ILAR J. 2014;55(3):418-26.

Hooijmans CR, Rovers MM, de Vries RB, Leenaars M, Ritskes-Hoitinga M, Langendam MW. SYRCLE’s risk of bias tool for animal studies. BMC Med Res Methodol. 2014;14:43.

Ritskes-Hoitinga M, Leenaars M, Avey M, Rovers M, Scholten R. Systematic reviews of preclinical animal studies can make significant contributions to health care and more transparent translational medicine. Cochrane Database Syst Rev. 2014;3:ED000078.

Sloff M, de Vries R, Geutjes P, In’t Hout J, Ritskes-Hoitinga M, Oosterwijk E, et al. Tissue engineering in animal models for urinary diversion: a systematic review. PLoS One. 2014;9(6):e98734.

van Luijk J, Bakker B, Rovers MM, Ritskes-Hoitinga M, de Vries RB, Leenaars M. Systematic reviews of animal studies; missing link in translational research? PLoS One 2014;9(3):e89981.

Ritskes-Hoitinga Merel and Susan Green 2014. Rapid response in BMJ: http://www.bmj.com/%5Bfield_highwire_a_cpath-raw%5D-15/rr/703339

Ritskes-Hoitinga M. Towards the future. Lab Anim. 2014 Jun 17;48(3):270. [Epub ahead of print] PubMed PMID: 24939968.

Wever KE, Hooijmans CR, Riksen NP, Sterenborg TB, Sena ES, Ritskes-Hoitinga M, Warlé MC. Determinants of the Efficacy of Cardiac Ischemic Preconditioning: A Systematic Review and Meta-Analysis of Animal Studies. PLoS One. 2015 Nov 18;10(11):e0142021.

Kleikers PW, Hooijmans C, Göb E, Langhauser F, Rewell SS, Radermacher K, Ritskes-Hoitinga M, Howells DW, Kleinschnitz C, Schmidt HH. A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation. Sci Rep. 2015 Aug 27;5:13428.

Hooijmans CR, Geessink FJ, Ritskes-Hoitinga M, Scheffer GJ. A systematic review and meta-analysis of the ability of analgesic drugs to reduce metastasis in experimental cancer models. Pain. 2015 Oct;156(10):1835-44.

Jonker SJ, Menting TP, Warlé MC, Ritskes-Hoitinga M, Wever KE. Preclinical Evidence for the Efficacy of Ischemic Postconditioning against Renal Ischemia-Reperfusion Injury, a Systematic Review and Meta-Analysis. PLoS One. 2016 Mar 10;11(3):e0150863. doi: 10.1371/journal.pone.0150863.

Hooijmans CR, Geessink FJ, Ritskes-Hoitinga M, Scheffer GJ. A Systematic Review of the Modifying Effect of Anaesthetic Drugs on Metastasis in Animal Models for Cancer. PLoS One. 2016 May 26;11(5):e0156152. doi: 10.1371/journal.pone.0156152.

Belgers M, Leenaars M, Homberg JR, Ritskes-Hoitinga M,Schellekens AF, Hooijmans CR. Ibogaine and addiction in the animal model, a systematic review and meta-analysis. Transl Psychiatry. 2016 May 31;6(5):e826. doi: 10.1038/tp.2016.71.

Hooijmans CR, Wever KE, Ritskes-Hoitinga M, Scheffer GJ. The usefulness of systematic reviews of animal studies: shooting the messenger. Paediatr Anaesth. 2016 Aug;26(8):852-3. doi: 10.1111/pan.12938.

Wever KE, Geessink FJ, Brouwer M, Tillema A, Ritskes-Hoitinga M. A systematic review of discomfort to toe or ear clipping in laboratory rodents. Lab Anim. 2017 Jan 1:23677217705912. doi: 10.1177/0023677217705912.

Hesen NA, Riksen NP, Aalders B, Ritskes-Hoitinga M, El Messaoudi S, Wever KE. A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction. PLoS One 2017, 23: 12(8): e0183664.

Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A et al. Letter to the editor – round table unites to tackle culture change in an effort to improve animal research reporting. BMC Veterinary Research 2017, 13: 314

Ritskes-Hoitinga M, Wever K. Improving the conduct, reporting, and appraisal of animal research. BMJ. 2018 Jan 10;360:j4935. doi: 10.1136/bmj.j4935.

Osborne N, Avey MT, Anestidou L, Ritskes-Hoitinga M, Griffin G. Improving animal research reporting standards: HARRP, the first step of a unified approach by ICLAS to improve animal research reporting standards worldwide. EMBO Rep. 2018 May;19(5). pii: e46069. doi: 10.15252/embr.201846069.

Pound P, Ritskes-Hoitinga M. Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail. J Transl Med. 2018 Nov 7;16(1):304. doi: 10.1186/s12967-018-1678-1.

Hollyer, TR, Bordoni Luca, Kousholt BS, Van Luijk J, Ritskes-Hoitinga M, Oestergaard L. The evidence for the physiological effects of lactate on the cerebral microcirculation: a systematic review. J. of Neurochemistry 2019. https://doi.org/10.1111/jnc.14633

Hooijmans CR, de Vries RBM, Ritskes-Hoitinga M, Rovers MM, Leeflang MM, IntHout J, Wever KE, Hooft L, de Beer H, Kuijpers T, Macleod MR, Sena ES, Ter Riet G, Morgan RL, Thayer KA, Rooney AA, Guyatt GH, Schünemann HJ, Langendam MW, GRADE Working Group. Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies. PLoS One. 2018 Jan 11;13(1):e0187271. doi: 10.1371/journal.pone.0187271.

Gabriel Natan Pires, Andréia Gomes Bezerra, Rob B M de Vries, Cathalijn H C Leenaars, Merel Ritskes-Hoitinga, Sergio Tufik, Monica Levy Andersen. Effects of experimental sleep deprivation on aggressive, sexual and maternal behaviour in animals: a systematic review protocol. BMJ Open Science 2018;2:e000041. doi:10.1136/bmjos-2017.

Cathalijn HC Leenaars, Elmar GM Pels, Ruud NJMA Joosten, Merel Ritskes-Hoitinga. Wistar rats do not show preference for either of two commonly used nutritionally sound food rewards in a T-maze. J. of Veterinary behaviour 2019; 31: 22-27.

Cathalijn HC Leenaars, C Kouwenaar, FR Stafleu, A Bleich, M Ritskes-Hoitinga, RBM de Vries, FLB meijboom. Animal to human translation: a systematic scoping review of reported concordance rates. J Transl Med 2019;17:223

Cathalijn HC Leenaars, RBM de Vries, A Herning, D Visser, D Holthaus, J Reijmer, J Elzinga, RWM Kempkes, C Punt, W Beumer, FLB Meijboom, M Ritskes-Hoitinga. Animal models for cystic fibrosis: a systematic search and mapping review of the literature – Part 1: genetic models. Laboratory Animals 2019. Aug 14:23677219868502. doi: 10.1177/0023677219868502

Judith AKR van Luijk, M Popa, J Swinkels, JML Menon, W Alkema, N Roeleveld, SE Hoffmann, V Schlünssen, D Mandrioli, M Ritskes-Hoitinga, PTJ Scheepers. Establishing a health-based recommended occupational exposure limit for nitrous oxide using experimental animal data – A systematic review protocol. Environmental Research 2019 Nov;178:108711. doi: 10.1016/j.envres.2019.108711.

Merel Ritskes-Hoitinga, Judith van Luijk. How can systematic reviews teach us more about the implementation of the 3Rs and animal welfare? Animals 2019;9:1163